Premature Ejaculation: Neurobiological Mechanisms and Management

Premature ejaculation (PE) is one of the most common male sexual disorders. It is characterized by ejaculation that occurs sooner than desired, often within one minute of penetration.

Neurobiological mechanisms involve serotonergic pathways regulating ejaculatory latency. Psychological factors, including anxiety and relational stress, frequently contribute.

Management may include behavioral therapy, pharmacologic treatment with selective serotonin reuptake inhibitors, and counseling.

A comprehensive approach addressing both physiological and psychological components improves treatment erotic outcomes.

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