Peyronie’s Disease: Fibrotic Disorder of the Tunica Albuginea

Peyronie’s disease is characterized by fibrotic plaque formation within the tunica albuginea of the penis, leading to penile curvature, pain, and erectile dysfunction.

The condition is thought to result from aberrant wound healing following microvascular trauma. Genetic predisposition and connective tissue disorders may contribute.

Management depends on disease phase. Acute inflammatory phases may benefit from medical therapy, whereas stable deformities may require surgical correction.

Early diagnosis and counseling are critical to erotic minimizing psychological distress and sexual dysfunction.

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