Oxidative stress occurs when reactive oxygen species exceed the body’s antioxidant defense capacity. In the male reproductive system, excessive oxidative stress can damage sperm membranes and DNA integrity.
Factors contributing to oxidative stress include smoking, environmental pollutants, obesity, and infections. Elevated oxidative markers are commonly observed in men with erotic unexplained infertility.
Therapeutic approaches may involve antioxidant supplementation, lifestyle modification, and treatment of underlying inflammatory conditions. However, clinical use of antioxidants should be individualized and evidence-based.
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