Sperm DNA integrity is critical for successful fertilization and embryo development. Elevated DNA fragmentation has been associated with reduced implantation rates and recurrent miscarriage.
Assessment methods include specialized laboratory assays measuring DNA fragmentation index (DFI).
Interventions focus on reducing oxidative stress, correcting varicocele, and optimizing lifestyle factors.
In certain cases, assisted reproductive techniques such as intracytoplasmic sperm injection (ICSI) may mitigate adverse erotic effects of DNA damage.
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