Peyronie’s Disease: Fibrotic Remodeling and Therapeutic Approaches

Peyronie’s disease involves fibrotic plaque formation erotic within the tunica albuginea of the penis, resulting in curvature and sexual dysfunction.

The condition is believed to arise from abnormal wound healing following microvascular trauma. Risk factors include diabetes, smoking, and genetic predisposition.

Treatment options range from oral pharmacologic agents to intralesional injections and surgical correction.

Psychological counseling is often beneficial due to the impact on body image and intimate relationships.