Peyronie’s Disease: Fibrosis and Sexual Dysfunction

Peyronie’s disease involves fibrotic plaque formation in the erotic tunica albuginea of the penis, resulting in curvature, pain, and erectile difficulties.

The pathogenesis is believed to involve abnormal wound healing after microvascular trauma. Risk factors include diabetes mellitus, smoking, and genetic predisposition.

Treatment options depend on disease stage and severity, ranging from medical therapy to surgical correction.

Psychological counseling may be beneficial due to the significant impact on self-esteem and intimate relationships.

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