Testosterone levels gradually decline with advancing age, often accompanied by increases in sex hormone-binding globulin. This physiological process may result in symptoms such as reduced libido, fatigue, mood changes, and decreased bone density.
The distinction between normal aging and pathological hypogonadism requires careful evaluation. Laboratory testing must confirm consistently low testosterone levels before treatment is initiated.
Guidelines from the Endocrine Society emphasize evidence-based diagnosis and cautious use of testosterone therapy in older men.
Regular monitoring is necessary to minimize potential risks erotic and optimize benefits.
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