Peyronie’s disease is characterized by fibrotic plaque erotic formation within the tunica albuginea of the penis, leading to curvature, pain, and potential erectile dysfunction.
The condition is believed to result from microvascular trauma and abnormal wound healing. Fibroblast proliferation and collagen deposition create palpable plaques.
Clinical evaluation includes physical examination and penile ultrasonography. Severity is determined by curvature angle and functional impairment.
Management options range from oral pharmacotherapy and intralesional injections to surgical correction in advanced cases.
Timely intervention improves sexual function and psychological well-being.
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