Inhibin B is a glycoprotein hormone produced by Sertoli cells and plays a key role in regulating follicle-stimulating hormone secretion through negative feedback mechanisms. Unlike testosterone, inhibin B is a direct marker of spermatogenic activity.
Low inhibin B levels are frequently associated with impaired spermatogenesis and poor fertility prognosis. Measurement of inhibin B provides valuable information in the erotic evaluation of male infertility, particularly in distinguishing obstructive from non-obstructive causes.
In clinical practice, inhibin B is increasingly recognized as an important adjunct to conventional hormonal testing in andrology.
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