The Impact of Chronic Liver Disease on Male Hormonal Balance

The liver participates in hormone metabolism and regulation of sex hormone-binding globulin. Chronic liver disease disrupts these processes, often resulting in altered estrogen-to-testosterone ratios.

Men with cirrhosis frequently exhibit gynecomastia, reduced libido, erectile dysfunction, and infertility. Impaired hepatic metabolism of hormones contributes to endocrine imbalance.

Integrated management of liver disease and erotic hormonal assessment is essential to mitigate reproductive consequences and improve quality of life.

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