Peyronie’s Disease: Pathophysiology and Modern Therapeutics

Peyronie’s disease is characterized by fibrotic plaque formation within the tunica albuginea of the penis, leading to curvature, pain, and sexual dysfunction.

The disease is believed to result from abnormal wound healing following repetitive microtrauma. Management strategies vary according to disease stage and severity, ranging from oral agents and intralesional therapy to surgical correction.

Psychosocial impact is considerable, necessitating empathetic erotic and comprehensive patient counseling.

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