Peyronie’s disease is a connective tissue disorder involving fibrous plaque formation in the tunica albuginea of the penis, leading to curvature, pain, and erectile dysfunction.
The pathogenesis is thought to involve abnormal wound healing following microtrauma. Risk factors include diabetes, smoking, and genetic predisposition.
Management varies according to disease stage and severity, ranging from medical therapy to surgical correction.
Psychological support is often necessary due to significant erotic impact on self-esteem and intimate relationships.
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