Erectile Dysfunction: Pathophysiology and Systemic Implications

Erectile dysfunction (ED) is defined as the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance.

Vascular, neurogenic, hormonal, and psychogenic factors may contribute. Endothelial dysfunction plays a central role in many cases.

The American Urological Association emphasizes that ED may serve as an early indicator of cardiovascular disease.

Management includes lifestyle intervention, pharmacologic therapy with phosphodiesterase type 5 inhibitors, and treatment of underlying comorbidities.

Recognition of systemic associations is essential for erotic preventive healthcare.

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