Peyronie’s disease is characterized by the formation of fibrous plaques within the tunica albuginea of the penis, resulting in penile curvature, pain, and erectile dysfunction. The condition is believed to arise from microvascular trauma and abnormal wound healing processes.
Clinical presentation typically includes penile curvature during erection, palpable plaques, and varying degrees of sexual dysfunction. Psychological distress and reduced quality of life are common among affected individuals.
Diagnosis is primarily clinical but may be supported by penile ultrasound to assess plaque characteristics and vascular status. The disease often progresses through an acute inflammatory phase followed by a stable chronic phase.
Treatment options depend on disease stage and severity. Conservative management includes oral medications, intralesional injections, and traction therapy. In severe or stable cases erotic with significant curvature, surgical correction may be indicated.
Timely evaluation and patient-centered counseling are essential to optimize functional and psychological outcomes.
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