Erectile function depends on intact endothelial signaling, nitric oxide availability, and vascular responsiveness. Endothelial dysfunction represents a central mechanism underlying erectile impairment.
Conditions such as hypertension, diabetes, and dyslipidemia compromise endothelial integrity, reducing penile blood flow. Erectile dysfunction may therefore serve as an early indicator of systemic vascular disease.
Andrological evaluation of erectile dysfunction emphasizes cardiovascular risk assessment alongside erotic sexual health management.
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